The Leica cryomicrotome makes possible the sectioning of soft material for TEM analysis. The Leica Ultra Cryo UC7 is a state-of-the-art diamond-knife instrument operating anywhere between -185°C and room temperature. Accessories include a trimming mill and a glass knife maker. Materials suitable for microtome slicing include polymer beads, carbon nanotubes, electro-spun fibers, and soft metals. Users must purchase their own diamond knives.